EVALUATION OF ORAL BACTERIA AS RISK INDICATORS FOR PERIODONTITIS IN OLDER ADULTS
EVALUATION OF ORAL BACTERIA AS RISK INDICATORS FOR PERIODONTITIS IN OLDER ADULTS
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DOI：
10.1902/jop.1992.63.2.93
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发表时间：
1992-02-01
影响因子：
4.3
通讯作者：
TUDOR, GE
中科院分区：
文献类型：
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作者：
BECK, JD;KOCH, GG;TUDOR, GE
随机抽取366名黑人和297名白色社区居民，年龄在65岁或以上，居住在北卡罗来纳州的5个县。 此外，窝藏这些微生物的网站和附件（LA）和口袋深度（PD）的损失之间的关系提出的方式，认为缺乏独立的网站内每个人。 在家庭访问期间，由经过培训的检查员测量所有牙齿的袋深度和衰退。 免疫荧光法检测A.使用纸尖对从四个第一磨牙的近颊面获得的龈下菌斑样品进行放线菌共生菌、中间普氏菌和牙龈普氏菌的检测。 A.伴放线菌、中间普氏菌和牙龈普氏菌在黑人中的阳性率高于白人。 最显著的差异是牙龈卟啉单胞菌，在38.8%的黑人和9.4%的白人中发现。 当评估这些生物体的位点百分比时，发现了类似的关系。 与未感染牙龈卟啉单胞菌或中间卟啉单胞菌的黑人相比，感染牙龈卟啉单胞菌或中间卟啉单胞菌的黑人LA大于或等于7 mm的部位的患病率更高。 白人也是如此。 牙龈卟啉单胞菌或中间卟啉单胞菌与PD大于或等于6 mm之间的关系在黑人和白人中都有发现。 然而，当两者均感染牙龈卟啉单胞菌或中间卟啉单胞菌时，黑人LA大于或等于7 mm或PD大于或等于6 mm的患病率高于白人，这是提示性趋势而非显著性趋势。 最后，LA大于或等于7 mm的逻辑回归模型显示，当牙龈卟啉单胞菌、中间卟啉单胞菌、最后一次看牙医时间超过3年以及烟草使用已经在模型中时，种族不再是显著的解释变量。 很明显，破坏性牙周病是龈下微生物区系和非细菌因素之间复杂关系的结果。 微生物植物群和这些其他因素之间的相互作用提出了一个富有成效的调查领域，以充分了解成人牙周病的复杂性。
THE PREVALENCE OF PEOPLE AND SITES WITH ATTACHMENT LOSS, pocket depth, Actinobacillus actinomycetemcomitans, Prevotella intermedia, and Porphyromonas gingivalis are described for a random sample of 366 black and 297 white community-dwelling adults, aged 65 or over, residing in five counties in North Carolina. In addition, relationships between sites harboring these microorganisms and loss of attachment (LA) and pocket depth (PD) are presented in a manner that considers the lack of independence of sites within each person. Pocket depths and recession were measured on all teeth by trained examiners during household visits. Immunofluorescent assays for A. actinomycetemcomitans, P. intermedia, and P. gingivalis were conducted on subgingival plaque samples obtained from the mesiobuccal aspect of the four first molar teeth using paper points. The prevalences of A. actinomycetemcomitans, P. intermedia, and P. gingivalis were greater in blacks than in whites. The most striking difference was seen for P. gingivalis, which was found in 38.8% of blacks and 9.4% of whites. Similar relationships were found when the percent of sites with these organisms were assessed. Blacks with P. gingivalis or P. intermedia had a higher prevalence of sites with LA greater-than-or-equal-to 7 mm as compared to blacks not infected with P. gingivalis or P. intermedia. The same was true for whites. Similar relationships between P. gingivalis or P. intermedia and PD greater-than-or-equal-to 6 mm were found for both blacks and whites. However, the greater prevalence for blacks than whites for LA greater-than-or-equal-to 7 mm or PD greater-than-or-equal-to 6 mm when both were infected with P. gingivalis or P. intermedia were suggestive trends rather than significant. Finally, a logistic regression model for LA greater-than-or-equal-to 7 mm showed that race was no longer a significant explanatory variable when P. gingivalis, P. intermedia, last visit to the dentist being more than 3 years ago, and tobacco use were already in the model. It is clear that destructive periodontal disease is the result of a complex relationship among subgingival microflora and non-bacterial factors. The interaction between the microbial flora and these other factors present a fruitful area of investigation in order to fully understand the complexity of periodontal disease in adults.