Standard Review Cold-active microbial Lipases: a versatile tool for industrial applications
Standard Review Cold-active microbial Lipases: a versatile tool for industrial applications
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发表时间：
2007
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通讯作者：
Babu Joseph;P. Ramteke;G. Thomas;N. Shrivastava
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作者：
Babu Joseph;P. Ramteke;G. Thomas;N. Shrivastava
脂肪酶是一类催化长链甘油三酯水解的酶，是生物技术应用中最重要的一类生物催化剂。近年来，由于冷活性脂肪酶在手性中间体有机合成中的应用越来越广泛，引起了人们的关注。由于其较低的最适温度和极低温度下的高活性，这是生产相对脆弱的化合物的有利性质。冷活性脂肪酶是当今有机化学家、药剂师、生物物理学家、生化和工艺工程师、生物技术学家、微生物学家和生物化学家的首选酶。综述了冷活性微生物脂肪酶在医疗制药、精细化工合成、食品工业、家庭和环境等方面的应用。
Lipases are a class of enzymes which catalyze the hydrolysis of long chain triglycerides and constitute the most important group of biocatalysts for biotechnological applications. Cold active lipases have lately attracted attention as a result of their increasing use in the organic synthesis of chiral intermediates. Due to their low optimum temperature and high activity at very low temperatures, which are favorable properties for the production of relatively frail compounds. Cold active lipases are today the enzymes of choice for organic chemists, pharmacists, biophysicists, biochemical and process engineers, biotechnologists, microbiologists and biochemists. The present review describes various industrial applications of cold active microbial lipases in the medical and pharmaceuticals, fine chemical synthesis, food Industry, domestic and environmental applications.