Catalytic atom-transfer radical cyclization by copper/bipyridine species encapsulated in polysiloxane gel.
Catalytic atom-transfer radical cyclization by copper/bipyridine species encapsulated in polysiloxane gel.
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DOI：
10.1039/b923213c
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发表时间：
2010-03
影响因子：
4.9
通讯作者：
Yukihiro Motoyama;Kazuyuki Kamo;A. Yuasa;H. Nagashima
中科院分区：
文献类型：
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作者：
Yukihiro Motoyama;Kazuyuki Kamo;A. Yuasa;H. Nagashima
在Karstedt催化剂存在下，用4，4 ′-双[（2-丙烯基）氧基]-2，2 ′-联吡啶和1，5-己二胺处理聚甲基氢硅氧烷，然后加入CuCl，制备了一种新型的聚硅氧烷凝胶，其中固定了CuCl/联吡啶物种。该聚硅氧烷凝胶在α-卤代乙酰胺衍生物的原子转移自由基环化中以高转换数起可重复使用的催化剂的作用，而不允许金属物质泄漏。
Novel polysiloxane gel, in which CuCl/bipyridine species are immobilized, is prepared by treatment of polymethylhydrosiloxane with 4,4'-bis[(2-propenyl)oxy]-2,2'-bipyridine and 1,5-hexadine in the presence of Karstedt's catalyst followed by addition of CuCl. This polysiloxane gel acts as a reusable catalyst in the atom-transfer radical cyclization of alpha-halogenated acetamide derivatives in high turnover numbers without allowing leakage of the metal species.