Primary Localized Orbital Amyloidosis Composed of the Immunoglobulin γ Heavy Chain CH3 Domain
Primary Localized Orbital Amyloidosis Composed of the Immunoglobulin γ Heavy Chain CH3 Domain
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由免疫球蛋白 γ 重链 CH3 结构域组成的原发性局限性眼眶淀粉样变性
DOI：
10.1042/cs0870487
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发表时间：
1994
期刊：
影响因子：
6
通讯作者：
M. Pepys
中科院分区：
文献类型：
--
作者：
S. Tan;I. Murdoch;T. Sullivan;J. Wright;O. Truong;J. Hsuan;P. Hawkins;M. Pepys
1. 原发性眼眶淀粉样变性是一种罕见的局限性淀粉样变性，其前体蛋白此前尚未被鉴定。我们在这里报告了首次从含有眼眶淀粉样蛋白的组织活检中提取淀粉样蛋白原纤维，并对原纤维蛋白进行表征。
1. Primary orbital amyloidosis is a rare form of localized amyloidosis in which the precursor protein has not previously been identified. We report here the first extraction of amyloid fibrils from a tissue biopsy containing orbital amyloid, and characterization of the fibril protein.