Clinical correlates of acoustic neuroma volume.
Clinical correlates of acoustic neuroma volume.
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听神经瘤体积的临床相关性。
DOI：
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发表时间：
1993
期刊：
影响因子：
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通讯作者：
R. Nelson
中科院分区：
文献类型：
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作者：
M. Arriaga;S. Long;R. Nelson
一种计算机辅助的、基于MRI的肿瘤体积测定技术被用于将术前听力水平和术后长期面部功能与听神经瘤体积相关联。术前听力进行了研究，在一组41例患者进行直接的肿瘤体积计算，并在另一组131例患者的体积外推的听神经瘤体积直径的关系。类似地，在另外864例长期随访的患者中，术后面部功能与听神经瘤体积相关。发现术前听力水平与肿瘤体积无显著相关性。然而，术后面部功能与肿瘤体积显著相关，最好预测为直径的非线性函数。因此，肿瘤体积的变化是临床治疗听神经瘤的重要考虑因素。应告知患者，即使是肿瘤直径的微小变化（尤其是较大的肿瘤）也可能导致肿瘤体积变化，这可能与术后面部功能的显著变化相关。
A computer-assisted, MRI-based technique of tumor volume determination was used to correlate preoperative hearing levels and long-term postoperative facial function with acoustic neuroma volume. Preoperative hearing was studied in a group of 41 patients subjected to direct tumor volume calculations and in another group of 131 patients in whom volume was extrapolated from the acoustic neuroma volume-diameter relation. Similarly postoperative facial function was correlated with acoustic neuroma volume in another 864 patients in whom long-term follow-up was available. Preoperative hearing levels were found not to be significantly related to tumor volume. However, postoperative facial function was significantly associated with tumor volume and was best predicted as a nonlinear function of diameter. Thus, tumor volume changes are important considerations in the clinical management of acoustic neuromas. Patients should be advised that even small changes in tumor diameter (especially in larger tumors) can result in tumor volume changes that may be associated with significant changes in postoperative facial function.