CANCER MORTALITY AMONG WORKERS EXPOSED TO ZINC CHROMATE PAINTS
CANCER MORTALITY AMONG WORKERS EXPOSED TO ZINC CHROMATE PAINTS
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DOI：
10.1097/00043764-198001000-00008
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发表时间：
1980-01-01
影响因子：
3.2
通讯作者：
PAYNE, WW
中科院分区：
文献类型：
--
作者：
DALAGER, NA;MASON, TJ;PAYNE, WW
为评估铬化合物在使用行业中的致癌性，对飞机维修行业中接触铬酸锌底漆的喷漆工和接触铬酸的电镀工的相应死亡情况进行了研究。与美国白人男性的死亡模式相比，在48名电镀工的死亡案例中未发现癌症过量情况。对202名喷漆工死亡案例的分析显示癌症显著过量，主要是呼吸道癌症。呼吸道癌症的相对增加与估计的接触时间长度呈正相关，且仅限于从首次就业到死亡间隔至少20年的喷漆工。这些研究结果与职业接触铬化合物相符，此前已表明铬化合物在制造过程中具有致癌性，但不能排除其他油漆成分、吸烟或方法学局限性的影响。
To evaluate the carcinogenicity of Cr compounds among user industries, the proportionate mortality experience of spray painters exposed to zinc chromate primer paints and electroplaters exposed to chromic acid in the aircraft maintenance industry was examined. Compared to the mortality patterns of U.S. white males, no excess of cancer was found in the 48 deaths among electroplaters. Analysis of the 202 deaths among spray painters revealed a significant excess of cancer, primarily of the respiratory tract. The relative increase of respiratory cancer showed a positive gradient with the length of estimated exposure time, and was confined to painters whose interval from first employment to death was at least 20 yr. The findings are consistent with occupational exposure to Cr compounds, previously shown to be carcinogenic in manufacturing processes, but the effect of other paint constituents, tobacco smoking or methodologic limitations could not be discounted.