Integration of olfactory information in a spatial representation enabling accurate arm choice in the radial arm maze
Integration of olfactory information in a spatial representation enabling accurate arm choice in the radial arm maze
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DOI：
10.1101/lm.2.6.299
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发表时间：
1996-01-01
影响因子：
2
通讯作者：
Schenk, F
中科院分区：
文献类型：
--
作者：
Lavenex, P;Schenk, F
本研究的目的是确定大鼠是否以及如何使用局部嗅觉线索进行空间定位，在不同的条件下对大鼠进行八臂径向迷宫的训练，这些条件是通过是否存在标记每只臂的辅助嗅觉线索、远处视觉空间信息的可用性以及迷宫的照明（亮或暗）来定义的。不同的视觉条件旨在区分光本身的影响和视觉空间线索的影响，使用嗅觉线索进行准确的手臂选择，使用修改嗅觉线索排列的不同程序来确定大鼠是否形成嗅觉线索的空间配置的表示，以及它们是否可以依赖这种表示在径向迷宫中进行准确的手臂选择。本研究表明，在径向臂迷宫中使用嗅觉线索来指导手臂选择很大程度上取决于照明条件，并且意味着根据光的存在或不存在两种不同的嗅觉信息处理模式。嗅觉线索以明确的方式使用，并且仅在没有光的情况下才能准确选择手臂，然而，无论照明条件如何，大鼠对嗅觉线索的位置都有内隐记忆，并形成这些线索的空间位置的表示。他们并没有记住嗅觉线索本身的空间配置，而是需要将这些线索与外部空间参考系联系起来。
The aim of the present study was to determine whether and how rats can use local olfactory cues for spatial orientation, Rats were trained in an eight-arm radial maze under different conditions as defined by the presence or absence of supplementary olfactory cues marking each arm, the availability of distant visuospatial information, and the illumination of the maze (Light or darkness), The different visual conditions were designed to dissociate among the effects of Light per se and those of visuospatial cues, on the use of olfactory cues for accurate arm choice, Different procedures with modifications of the arrangement of olfactory cues were used to determine if rats formed a representation of the spatial configuration of the olfactory cues and if they could rely on such a representation for accurate arm choice in the radial maze. The present study demonstrated that the use of olfactory cues to direct arm choice in the radial arm maze was critically dependent on the illumination conditions and implied two different modes of processing of olfactory information according to the presence or the absence of light. Olfactory cues were used in an explicit manner and enabled accurate arm choice only in the absence of light, Rats, however, had an implicit memory of the location of the olfactory cues and formed a representation of the spatial position of these cues, whatever the Lighting conditions. They did not memorize the spatial configuration of the olfactory cues per se but needed these cues to be linked to the external spatial frame of reference.