HIGHLY PATHOGENIC PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS SUMMARY Etiology

HIGHLY PATHOGENIC PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS SUMMARY Etiology
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2016
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猪繁殖与呼吸综合征病毒(Porcine reproductive and respiratory syndrome virus,PRRSV)是一种有包膜的单链RNA病毒,属于动脉炎病毒科。该家族的其他成员包括马动脉炎病毒、乳酸脱氢酶升高病毒(LDV)和猿猴出血热病毒。·20世纪80年代末,PRRSV在美国和德国几乎同时出现,导致猪严重的生殖和呼吸系统疾病。高致病性PRRSV(HP-PRRSV)于2006年在中国首次被描述,当时爆发了200万头猪受到影响,40万头死亡。该病毒起源于已经在中国流行的2型(北美)PRRSV。新的HP-PRRSV继续出现,高致病性病毒形式目前在中国占主导地位。
Etiology • Porcine reproductive and respiratory syndrome virus (PRRSV) is an enveloped, single-stranded RNA virus within the family Arteriviridae. Other members of the family include equine arteritis virus, lactate dehydrogenase-elevating virus (LDV), and simian hemorrhagic fever virus. • PRRSV emerged almost simultaneously in the late 1980s in the U.S. and Germany, causing severe reproductive and respiratory disease in pigs. • Highly pathogenic PRRSV (HP-PRRSV) was first described in China in 2006, following an outbreak in which 2 million pigs were affected and 400,000 died. The virus originated from a type 2 (North American) PRRSV already circulating in China. New HP-PRRSVs continue to emerge and highly pathogenic forms of the virus are now dominant in China.