Fabrication of low-cost electronic biosensors
Fabrication of low-cost electronic biosensors
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DOI：
10.1016/s1369-7021(09)70247-0
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发表时间：
2009-09-01
期刊：
影响因子：
24.2
通讯作者：
Bao, Zhenan
中科院分区：
文献类型：
--
作者：
Sokolov, Anatoliy N.;Roberts, Mark E.;Bao, Zhenan
通过高通量技术（例如印刷）制造基于有机电子器件的小型化、低成本、柔性传感器预计将为化学和生物检测中的应用提供重要益处。有机电子领域合成方法的快速成熟导致了新材料以令人难以置信的速度产生，并增加了对荧光体-分析物相互作用的理解。由于这些进步，我们已经看到了稳定的提高，灵敏度，稳定性和特异性，除了检测范围广泛的化学分析物。在这篇综述中，我们将讨论基于有机晶体管的检测设备的制造、挑战和传感器性能，并展望开发能够在生物相关介质中工作的传感器。
The fabrication of miniaturized, low-cost, flexible sensors based on organic electronics via high-throughput techniques (e.g. printing) is expected to provide important benefits for applications in chemical and biological detection. The rapid maturation of synthetic methodology in the field of organic electronics has lead to the creation of new materials at an incredible rate and an increased understanding of semiconductor-analyte interactions. Owing to these advances, we have seen steady improvements in sensitivity, stability, and specificity, in addition to the detection of a wide range of chemical analytes. In this review, we address the fabrication, challenges, and sensor performance of organic transistor-based detection devices with an outlook toward developing sensors capable of operating in biologically relevant media.