Mindfulness-Based Cognitive Therapy Improves Polysomnographic and Subjective Sleep Profiles in Antidepressant Users with Sleep Complaints
Mindfulness-Based Cognitive Therapy Improves Polysomnographic and Subjective Sleep Profiles in Antidepressant Users with Sleep Complaints
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DOI：
10.1159/000332755
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发表时间：
2012-01-01
影响因子：
22.8
通讯作者：
Bootzin, Richard R.
中科院分区：
文献类型：
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作者：
Britton, Willoughby B.;Haynes, Patricia L.;Bootzin, Richard R.
背景资料：许多抗抑郁药物（ADM）与睡眠连续性中断有关，这可能会影响药物依从性并阻碍成功治疗。本研究调查了正念冥想（MM）训练是否可以改善抑郁症患者的自我报告和客观测量的多导睡眠图（PSG）睡眠曲线，这些患者至少部分缓解了ADM，但仍然有残余的睡眠投诉。研究方法：23名有睡眠问题的ADM使用者被随机分为8周的正念认知治疗（MBCT）课程或等待控制条件。前后测量包括PSG睡眠研究和主观报告的睡眠，残余抑郁症状。结果：与对照组相比，MBCT参与者在PSG和睡眠主观测量方面都有所改善。他们表现出一种减少觉醒时间和提高睡眠效率的模式。睡眠深度，如第一阶段和慢波睡眠所测量的，并没有因为正念训练而改变。结论：MM与ADM使用者客观和主观测量的睡眠连续性增加相关。MM训练可能是更可取的和成本效益的替代中断或补充催眠药，并可能有助于更可持续地从抑郁症中恢复。版权所有（c）2012 S. Karger AG，巴塞尔
Background: Many antidepressant medications (ADM) are associated with disruptions in sleep continuity that can compromise medication adherence and impede successful treatment. The present study investigated whether mindfulness meditation (MM) training could improve self-reported and objectively measured polysomnographic (PSG) sleep profiles in depressed individuals who had achieved at least partial remission with ADM, but still had residual sleep complaints. Methods: Twenty-three ADM users with sleep complaints were randomized into an 8-week Mindfulness-Based Cognitive Therapy (MBCT) course or a waitlist control condition. Pre-post measurements included PSG sleep studies and subjectively reported sleep, residual depression symptoms. Results: Compared to controls, the MBCT participants improved on both PSG and subjective measures of sleep. They showed a pattern of decreased wake time and increased sleep efficiency. Sleep depth, as measured by stage 1 and slow-wave sleep, did not change as a result of mindfulness training. Conclusions: MM is associated with increases in both objectively and subjectively measured sleep continuity in ADM users. MM training may serve as more desirable and cost-effective alternative to discontinuation or supplementation with hypnotics, and may contribute to a more sustainable recovery from depression. Copyright (c) 2012 S. Karger AG, Basel