THE MICROSCOPIC DETERMINATION OF AGE IN HUMAN-BONE
THE MICROSCOPIC DETERMINATION OF AGE IN HUMAN-BONE
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DOI：
10.1002/ajpa.1330230215
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发表时间：
1965-01-01
影响因子：
2.8
通讯作者：
KERLEY, ER
中科院分区：
文献类型：
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作者：
KERLEY, ER
通过计数骨块、骨碎片和非哈弗斯管的数量，并估计股骨、胫骨和腓骨中段地面切片中选定的4个皮质外1/3的100倍视野中板层骨的百分比，测量了人类皮质骨的微观年龄变化。年龄图来自126个样本，涵盖了从出生到95岁的年龄范围。回归分析发现，腓骨骨碎片数与年龄相关性最好(p=9.74)。使用这一因素的回归公式，95%的时间可以在实际年龄的[正负]十年内估计年龄。另一种方法是利用专门设计的轮廓图从年龄变化图中估计年龄。当对另外56个样本进行检查时，87.3%的估计值在实际年龄的[正负]五年内，所有的估计值都在[正负]十年内。结论是，在腿的主要长骨的皮质中有可测量的微观年龄变化，可以用来估计一个人从出生到95岁的整个范围内的已知准确性。这种方法可以应用于碎裂和不完整的骨骼以及被侵蚀的考古骨骼，因为只使用了腿骨的中轴。
The microscopic age changes that occur in human cortical bone were measured by counting the number of osteones, osteon fragments and non-Haversian canals, and estimating the percentage of lamellar bone in four selected 100 power fields in the outer third of the cortex in ground sections from the mid- shaft of the femur, tibia and fibula. Age graphs were derived from 126 specimens covering the age range from birth through 95 years. The best correlation with age by regression analysis was found in the osteon fragment number in the fibula (p = 9.74). The use of the regression formula for this factor permits the age to be estimated within [plus or minus] ten years of the actual age 95% of the time. An alternative method utilizes a specially devised profile chart to estimate age from the age change graphs. When this method was checked on 56 additional specimens, 87.3% of the estimates were within [plus or minus] five years of the actual age, and all estimates were within [plus or minus] ten years. It was concluded that there are measurable microscopic age changes in the cortex of the major long bones of the leg that can be used to estimate the age of an individual with known accuracy over the entire range from birth to 95 years. This method can be applied to fragmented and incomplete skeletons as well as eroded archeologic skeletons, since only the mid-shafts of leg bones are used.