TRANSCRIPTION OF THE DROSOPHILA-WHITE LOCUS AND SOME OF ITS MUTANTS
TRANSCRIPTION OF THE DROSOPHILA-WHITE LOCUS AND SOME OF ITS MUTANTS
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DOI：
10.1002/j.1460-2075.1984.tb01847.x
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发表时间：
1984-01-01
期刊：
影响因子：
11.4
通讯作者：
BROCKL, C
中科院分区：
文献类型：
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作者：
PIRROTTA, V;BROCKL, C
白色基因座产生一个主要的，但罕见的，2.6 kb的RNA [核糖核酸酶]，发现整个发展。还产生了较低MW的次要物质。其中之一是男性特有的。通过北方印迹杂交分析野生型和几种突变体：wa、w 67 c23、we、wsp和zeste的转录。这些和S1定位的结果揭示了至少4个内含子的存在。其中之一是一个30-50个核苷酸的微内含子，包含wa突变体中copia插入的位点。
The white locus produces 1 major, though rare, RNA of 2.6 kb [kilobases], found throughout development. Minor species of lower MW are also produced. One of these is male specific. Transcription was analyzed by Northern blot hybridization in the wild-type and several mutants: wa, w67c23, we, wsp and zeste. These and the results of S1 mapping reveal the presence of at least 4 introns. One of these, a microintron of 30-50 nucleotides contains the site of copia insertion in the wa mutant.