CHARACTERIZATION AND INVIVO DISTRIBUTION OF TC-99M-LABELED AND IN-111-LABELLED MAGNETITE
CHARACTERIZATION AND INVIVO DISTRIBUTION OF TC-99M-LABELED AND IN-111-LABELLED MAGNETITE
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DOI：
10.1016/0883-2889(89)90092-0
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发表时间：
1989-01-01
影响因子：
1.6
通讯作者：
KELLY, JD
中科院分区：
文献类型：
--
作者：
BLIGH, SWA;SADLER, PJ;KELLY, JD
已制备出掺杂有 99mTc 或 111In 的直径为 0.1-0.5 μm 的磁铁矿 (Fe3O4) 颗粒，并通过电子显微镜和穆斯堡尔光谱进行了表征。确定了它们注射到大鼠体内后分布的时间进程，包括通过γ-相机成像进行的研究；主要目标是肝脏和肺。放射性标记的磁性剂在结合放射和磁共振成像程序的研究中可能具有价值。
Magnetite (Fe3O4) particles 0.1-0.5 .mu.m in diameter doped with either 99mTc or 111In have been prepared and characterized by electron microscopy and Mossbauer spectroscopy. The time courses of their distributions after injection into rats were determined, including studies by .gamma.-camera imaging; the main targets were the liver and lung. The radiolabelled magnetic agents may be of value in research studies combining radio- and magnetic resonance imaging procedures.