Sex hormone therapy and progression of cardiovascular disease in menopausal women.
Sex hormone therapy and progression of cardiovascular disease in menopausal women.
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绝经期妇女的性激素治疗和心血管疾病的进展。
DOI：
10.1042/cs20160042
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发表时间：
2016
期刊：
影响因子：
--
通讯作者：
Miller,VirginiaM
中科院分区：
文献类型：
--
作者：
Alhurani,RabeE;Chahal,CAnwarA;Ahmed,AhmedT;Mohamed,EssaA;Miller,VirginiaM
One of the most controversial health decisions facing women is deciding upon the use of hormonal treatments for symptoms of menopause. This brief review focuses on the historical context of use of menopausal hormone treatments (MHT), summarizes results of major observational, primary and secondary prevention studies of MHT and cardiovascular (CV) outcomes, provides evidence for how sex steroids modulate CV function and identifies challenges for future research. As medicine enters an era of personalization of treatment options, additional research into sex differences in the aetiology of CV diseases will lead to better risk identification for CV disease in women and identify whether a woman might receive CV benefit from specific formulations and doses of MHT.
