STRUCTURAL STUDIES ON THE CONNECTIVITY OF THE INFERIOR MESENTERIC GANGLION OF THE GUINEA-PIG
STRUCTURAL STUDIES ON THE CONNECTIVITY OF THE INFERIOR MESENTERIC GANGLION OF THE GUINEA-PIG
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DOI：
10.1016/0165-1838(82)90070-4
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发表时间：
1982-01-01
期刊：
影响因子：
--
通讯作者：
ELFVIN, LG
中科院分区：
文献类型：
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作者：
DALSGAARD, CJ;ELFVIN, LG
将辣根过氧化物酶（HRP）注射到豚鼠肠系膜下神经节（IMG）后，在T13-L4水平的太阳神经丛神经节、盆腔神经节、结状神经节以及脊髓和背根神经节中发现标记的细胞体。通过使用荧光示踪剂 True blue，还可以在远端结肠的肌间神经节和粘膜下神经节中检测到标记的细胞体。结肠神经对 HRP 的应用和摄取导致背根神经节、IMG 和太阳神经丛神经节复合体中的细胞体被标记，表明后者神经元将其在肠系间神经中的轴突通过 IMG 发送到结肠神经中继续到达远端结肠。当 HRP 被应用并扩散到腹下神经时，在 IMG、背根神经节和腰脊髓的节前核中看到标记的细胞体，其中 50% 的标记神经元位于中央管的背侧和背外侧。 IMG 神经供应的这种多样性表明神经节在内脏反射的整合中发挥着重要作用。
After injection of horseradish peroxidase (HRP) into the inferior mesenteric ganglion (IMG) of the guinea pig, labeled cell bodies were found in the solar plexus ganglia, the ganglia of the pelvic plexus, the nodose ganglia and in the spinal cord and dorsal root ganglia at the T13-L4 levels. By using the fluorescent tracer True blue, labeled cell bodies could also be detected in the myenteric and submucosa ganglia of the distal colon. Application and uptake of HRP by the colonic nerves resulted in labeling of cell bodies in the dorsal root ganglia, the IMG and in the solar plexus ganglion complex indicating that the latter neurons send their axons in the intermesenteric nerve through the IMG to continue in the colonic nerves to the distal colon. When HRP was applied and diffused into the hypogastric nerves labeled cell bodies were seen in the IMG, the dorsal root ganglia and in the preganglionic nuclei of the lumbar spinal cord with 50% of the labeled neurons located dorsal and dorsolateral to the central canal. Such a diversity in the nerve supply to the IMG, suggests that the ganglion plays an important role in the integration of visceral reflexes.