Cylindrical Micelles by the Self-Assembly of Crystalline-b-Coil Polyphosphazene-b-P2VP Block Copolymers. Stabilization of Gold Nanoparticles
Cylindrical Micelles by the Self-Assembly of Crystalline-b-Coil Polyphosphazene-b-P2VP Block Copolymers. Stabilization of Gold Nanoparticles
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DOI：
10.3390/molecules24091772
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发表时间：
2019-05-01
期刊：
影响因子：
4.6
通讯作者：
Presa Soto, Alejandro
中科院分区：
文献类型：
--
作者：
de los Angeles Cortes, Maria;de la Campa, Raquel;Presa Soto, Alejandro
在过去的几年里，人们开发了多种基于半结晶嵌段共聚物的结晶驱动自组装（CDSA）工艺，以在溶液（胶束）中制备多种不同的纳米形态。本文提出了一种方便的合成方法，该方法结合了：（i）由有机锂官能化膦引发剂引发的2-乙烯基吡啶的阴离子聚合，（ii）由-PR 2Cl 2引发的亚氨基膦的阳离子聚合，（iii）由有机锂官能化膦引发剂引发的2-乙烯基吡啶的阴离子聚合，（iv）由-PR 2Cl 2引发的2-乙烯基吡啶的阳离子聚合，（iv）由-PR 2Cl 2引发的2-乙烯基吡啶的阳离子聚合，（iv）由-PR 2Cl 2引发的2-乙烯基吡啶的阳离子聚合。和（iii）大分子亲核取代步骤，以制备新型嵌段共聚物聚（双三氟乙氧基磷腈）-b-聚（2-乙烯基吡啶）（PTFEP-b-P2 VP），其具有半结晶PTFEP核形成嵌段。这些材料在THF（四氢呋喃）和2-丙醇（P2 VP的选择性溶剂）的混合物中的自组装导致取决于所添加的2-丙醇的量的不同长度的各种圆柱形胶束。我们证明了PTFEP在胶束核心的结晶是控制自组装过程的主要因素。在胶束的冠的吡啶基部分的存在下，利用稳定的金纳米粒子（AuNPs）。
During the last number of years a variety of crystallization-driven self-assembly (CDSA) processes based on semicrystalline block copolymers have been developed to prepare a number of different nanomorphologies in solution (micelles). We herein present a convenient synthetic methodology combining: (i) The anionic polymerization of 2-vinylpyridine initiated by organolithium functionalized phosphane initiators; (ii) the cationic polymerization of iminophosphoranes initiated by -PR2Cl2; and (iii) a macromolecular nucleophilic substitution step, to prepare the novel block copolymers poly(bistrifluoroethoxy phosphazene)-b-poly(2-vinylpyridine) (PTFEP-b-P2VP), having semicrystalline PTFEP core forming blocks. The self-assembly of these materials in mixtures of THF (tetrahydrofuran) and 2-propanol (selective solvent to P2VP), lead to a variety of cylindrical micelles of different lengths depending on the amount of 2-propanol added. We demonstrated that the crystallization of the PTFEP at the core of the micelles is the main factor controlling the self-assembly processes. The presence of pyridinyl moieties at the corona of the micelles was exploited to stabilize gold nanoparticles (AuNPs).