Effects of hippocampal and parietal cortex lesions on the processing of multiple-object scenes
Effects of hippocampal and parietal cortex lesions on the processing of multiple-object scenes
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DOI：
10.1037/0735-7044.112.1.68
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发表时间：
1998-02-01
影响因子：
1.9
通讯作者：
Kesner, RP
中科院分区：
文献类型：
--
作者：
DeCoteau, WE;Kesner, RP
对大鼠进行3种多对象场景辨别实验中的1种。操作包括替换(基于对象)、置换(基于空间)或替换和置换(基于对象/空间)场景中的1个对象。一旦训练完成，大鼠接受海马区、顶叶皮质或皮质对照损毁，然后重新测试。顶叶皮质和海马区受损的大鼠在空间和对象/空间任务上都表现出缺陷，但在对象任务上没有。海马组在物体/空间任务上的缺陷只是暂时的，而顶叶皮质受损的大鼠在这两个任务中的损伤都是稳定的。顶叶皮质损伤的大鼠在物体/空间任务中遇到困难，可能表明他们无法转换认知策略。
Rats were taught 1 of 3 types of multiple-object scene discrimination. Manipulations included either replacing (object based), displacing (space based), or replacing and displacing (object/space based) 1 object in the scene. Once trained, rats received hippocampal, parietal cortex, or cortical control lesions and then were retested. Parietal cortex-and hippocampal-lesioned rats displayed deficits on both the space and object/space tasks but not the object task. The hippocampal-lesioned group's deficit on the object/space task was only transient, whereas the impairments of the parietal cortex-lesioned rats were stable for both tasks. The parietal cortex-lesioned rats sustained difficulty with the object/space task may indicate an inability to switch cognitive strategies.