Chiral palladacycle catalysts generated on a single-handed helical polymer skeleton for asymmetric arylative ring opening of 1,4-epoxy-1,4-dihydronaphthalene.
Chiral palladacycle catalysts generated on a single-handed helical polymer skeleton for asymmetric arylative ring opening of 1,4-epoxy-1,4-dihydronaphthalene.
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DOI：
10.1002/anie.201407358
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发表时间：
2014-11
影响因子：
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通讯作者：
Takeshi Yamamoto;Yuto Akai;M. Suginome
中科院分区：
文献类型：
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作者：
Takeshi Yamamoto;Yuto Akai;M. Suginome
聚(喹恶啉-2，3-二基)螺旋手性膦配体(PQXphos)与醋酸钯(II)聚合后C-H活化，定量得到手性磷环。在钯催化的1，4-环氧基-1，4-二氢萘与芳基硼酸的不对称开环芳基化反应中，原位生成的吡喃环对映体选择性高达94%ee。
Post-polymerization CH activation of poly(quinoxaline-2,3-diyl)-based helically chiral phosphine ligands (PQXphos) with palladium(II) acetate afforded chiral phosphapalladacycles quantitatively. In situ generated palladacycles exhibited enantioselectivities up to 94 % ee in the palladium-catalyzed asymmetric ring-opening arylation of 1,4-epoxy-1,4-dihydronaphthalenes with arylboronic acids.