Kinetic Study on Polymorphic Solid-State Transformation of Organic Compounds: Bisphenol A and DL-Methionine
Kinetic Study on Polymorphic Solid-State Transformation of Organic Compounds: Bisphenol A and DL-Methionine
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有机化合物双酚A和DL-蛋氨酸多晶型固态转化的动力学研究
DOI：
10.1252/jcej.35.247
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发表时间：
2002
期刊：
影响因子：
--
通讯作者：
M. Matsuoka
中科院分区：
文献类型：
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作者：
M. Yamanobe;H. Takiyama;M. Matsuoka
利用X射线衍射仪和差示扫描量热仪对双酚A(BPA)和DL-蛋氨酸(DL-Met)晶体进行了固态晶型转化实验。在作者提出的模型的基础上，讨论了转变的动力学和控制步骤。对于BPA，相变受控于早期稳定晶型的成核和生长，在充分成核后的生长阶段，而DL-Met的相变仅受生长步骤的控制。BPA和DL-Met在控制步骤上的差异归因于初始晶体中存在的稳定相的核数。这一点得到了机械应力双酚A晶体的额外实验的支持，在这些实验中，转变的控制步骤被改变为生长受限。这些结果表明所提出的固态相变模型对描述不同类型的相变行为是有效的。
Solid-state polymorphic transformation of bisphenol A (BPA) and DL-methionine (DL-Met) crystals was carried out experimentally with XRD and DSC. The kinetics and the governing steps of transformation were discussed on the basis of a model proposed previously by the authors. For BPA, the transformation was found to be controlled by nucleation and growth of the stable polymorph in the early period followed by the growth step after sufficient nucleation had occurred, while the transformation of DL-Met was solely controlled by the growth step. The difference in the governing steps between BPA and DL-Met was attributed to the numbers of nuclei of the stable phase present in the initial crystals. This was supported by additional experiments with mechanically stressed BPA crystals in which the governing step of the transformation was changed to be growth-limited. These results showed the validity of the proposed model of solid-state transformation to describe different types of transformation behaviors.
产生生长激素的垂体腺瘤术后照射 18 年后肉瘤转化
DOI：
--
发表时间：
2018
期刊：
影响因子：
--
作者：
岡田正康;米岡有一郎;大石誠;藤井幸彦
通讯作者：
藤井幸彦