AUTONOMIC NERVOUS DYSFUNCTION IN PATIENTS ON LONG-TERM HEMODIALYSIS
AUTONOMIC NERVOUS DYSFUNCTION IN PATIENTS ON LONG-TERM HEMODIALYSIS
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DOI：
10.1159/000181599
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发表时间：
1979-01-01
期刊：
影响因子：
2.5
通讯作者：
HIRASAWA, Y
中科院分区：
文献类型：
--
作者：
TAJIRI, M;AIZAWA, Y;HIRASAWA, Y
12 名长期血液透析患者静息时的血浆多巴胺-β-羟化酶 (DBH) 活性水平显着低于健康的 8 人对照组； 28.3.+-. 7.2 和 13.6.+-。分别为 7.6 IU/l (P < 0.01)。将每个受试者的一只手浸入冷水（4℃）1分钟后，两组均观察到显着升高，6.1±。对照为 4.8 IU/l，对照为 1.6 .+-。患者组为 1.4 IU/l (P < 0.01)。当所有受试者的头部倾斜时，两组的活动均显着增加，但患者组的增加明显较小：5.8.+-。 4.8 和 1.1.+-。 2 组分别为 1.6 IU/l (P < 0.01)。建议长期血液透析患者存在自主神经功能障碍。
The level of plasma dopamine-.beta.-hydroxylase (DBH) activity in subjects at rest was significantly lower in 12 patients on long-term hemodialysis than in a healthy 8-member control group; 28.3 .+-. 7.2 and 13.6 .+-. 7.6 IU/l, respectively (P < 0.01). Following immersion of 1 hand of each subject into cold H2O (4.degree. C) for 1 min, a significant rise was observed in both groups, 6.1 .+-. 4.8 IU/l for the control and 1.6 .+-. 1.4 IU/l for the patient group (P < 0.01). Upon tilting up the head of all subjects, activity in both groups increased significantly, but a markedly smaller rise was found in the patient group: 5.8 .+-. 4.8 and 1.1 .+-. 1.6 IU/l for the 2 groups, respectively (P < 0.01). An autonomic nervous dysfunction in patients on long-term hemodialysis is suggested.