Evaluation of Skin Test Reactions in Patients with Non‐immediate Type Drug Eruptions
Evaluation of Skin Test Reactions in Patients with Non‐immediate Type Drug Eruptions
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非立即型药疹患者皮试反应的评估
DOI：
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发表时间：
1990
期刊：
影响因子：
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通讯作者：
H. Nakajima
中科院分区：
文献类型：
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作者：
J. Osawa;S. Naito;M. Aihara;K. Kitamura;Z. Ikezawa;H. Nakajima
对242例出现迟发性药疹的患者进行皮肤试验反应评估。197例患者中贴片试验阳性62例（31.5%），皮内试验阳性105例（89.7%）。黄斑丘疹（MP）型、多形性红斑（EM）型和红皮病（ED）型药疹的皮内试验阳性率高于湿疹（Ecz）型，而ED、Ecz型和抗惊厥药物性药疹的皮内试验阳性率较高。认为将斑贴试验与皮内试验相结合，可用于迟发性药疹病因药物的测定。
Skin test reactions were evaluated in 242 patients who appeared to develop delayed type drug eruptions from the clinical course. The patch testing was positive in 62 (31.5%) of 197 patients tested and the intradermal testing in 105 (89.7%) of 117 patients. The positive ratios of intradermal testing were higher in maculopapular (MP), erythema multiforme (EM), and erythrodermic (ED) types than in eczematous (Ecz) type drug eruptions, while those of patch testing were comparatively high in ED, Ecz type, and anticonvulsant‐induced drug eruptions. It is considered that the combination of patch testing and intradermal testing is useful for determination of causative drugs in delayed type drug eruptions.