Associations between pain and current smoking status among cancer patients
Associations between pain and current smoking status among cancer patients
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DOI：
10.1016/j.pain.2010.09.001
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发表时间：
2011-01-01
期刊：
影响因子：
7.4
通讯作者：
Jacobsen, Paul B.
中科院分区：
文献类型：
--
作者：
Ditre, Joseph W.;Gonzalez, Brian D.;Jacobsen, Paul B.
人们对吸烟与癌症症状加重和治疗副作用(如疼痛)之间所谓的联系的经验和临床兴趣日益增长。疼痛和吸烟在癌症患者中非常普遍，最近的证据表明，尽管确诊后仍继续吸烟的癌症患者比不吸烟的人感受到更大的痛苦。因此，这项横断面研究的主要目标是在224名即将开始化疗的癌症患者样本中，检查不同水平的吸烟状况与几种疼痛相关结果之间的关系。患者完成了疼痛严重程度、疼痛相关痛苦和疼痛相关干预的自我报告，以及人口统计学调查问卷。结果表明，尽管被诊断为癌症但仍继续吸烟的人报告的疼痛比从不吸烟的人更严重，F(2,215)=3.47，p<；0.05。与既往吸烟者或从不吸烟者相比，现在吸烟者报告的疼痛干扰也更大，F(2,215)=5.61，p<；.01。在既往吸烟者中，观察到疼痛严重程度与戒烟年数呈负相关，r(104)=.26，p<；.01。这些数据表明，尽管被诊断为癌症，但继续吸烟与更严重的疼痛和疼痛的干扰有关；然而，未来的研究有理由确定这种关系的方向性。(C)2010年国际疼痛研究协会。爱思唯尔出版，版权所有。
There is growing empirical and clinical interest in purported associations between smoking and the aggravation of cancer symptoms and treatment side effects, such as pain. Both pain and smoking are highly prevalent among persons with cancer, and there is recent evidence to suggest that cancer patients who continue to smoke despite their diagnosis experience greater pain than nonsmokers. Accordingly, the main goal of this cross-sectional study was to examine associations between multiple levels of smoking status and several pain-related outcomes among a sample of 224 cancer patients about to begin chemotherapy. Patients completed self-report measures of pain severity, pain-related distress, and pain-related interference, as well as a demographics questionnaire. Results indicated that persons who continued to smoke despite being diagnosed with cancer reported more severe pain than never smokers, F (2, 215) = 3.47, p < .05. Current smokers also reported greater interference from pain than either former or never smokers, F (2, 215) = 5.61, p < .01. Among former smokers, an inverse relation between pain severity and the number of years since quitting smoking was observed, r (104) = .26, p < .01. These data suggest that continued smoking despite a cancer diagnosis is associated with greater pain severity and interference from pain; however, future research is warranted to determine the directionality of this relationship. (C) 2010 International Association for the Study of Pain. Published by Elsevier B.V. All rights reserved.