Invasion of the alveolar-capillary barrier by Aspergillus spp.: therapeutic and diagnostic implications for immunocompromised patients with invasive pulmonary aspergillosis
Invasion of the alveolar-capillary barrier by Aspergillus spp.: therapeutic and diagnostic implications for immunocompromised patients with invasive pulmonary aspergillosis
复制标题
DOI：
10.1080/13693780802510232
复制
发表时间：
2009-01-01
期刊：
影响因子：
2.9
通讯作者：
Hope, William W.
中科院分区：
文献类型：
--
作者：
Hope, William W.
曲霉属是免疫功能低下患者发病和死亡的主要原因。本文综述了宿主防御机制、曲霉菌破坏肺泡-毛细血管屏障的机制及其对侵袭性肺曲霉病患者诊断和治疗的意义。
Aspergillus spp. are leading causes of morbidity and mortality in immunocompromised patients. This review provides an overview of host defenses, the mechanisms by which the alveolar-capillary barrier is breeched by Aspergillus, and the implications for diagnosis and treatment of patients with invasive pulmonary aspergillosis.