Molecular characterization of the first Aichi viruses isolated in Europe and in South America
Molecular characterization of the first Aichi viruses isolated in Europe and in South America
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DOI：
10.1007/s00705-005-0706-7
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发表时间：
2006-06-01
影响因子：
2.7
通讯作者：
Schreier, E.
中科院分区：
文献类型：
--
作者：
Oh, D. -Y.;Silva, P. A.;Schreier, E.
爱知病毒是一种与急性胃肠炎相关的小核糖核酸病毒，迄今为止仅在亚洲国家有报道。本研究报告了在来自德国和巴西的临床标本中首次发现的爱知病毒。对德国和巴西分离株的核苷酸序列进行了测定、分析，并与已知的爱知序列进行了比较。德国菌株被证明是基因组A的成员，而巴西菌株属于基因组B。为了初步评估爱知病毒在德国的流行病学重要性，对一组485份德国血清样本进行了爱知病毒抗体筛查，发现血清阳性率为76%。
The occurrence of Aichi virus, a picornavirus associated with acute gastroenteritis, has so far only been described in Asian countries. This study reports the first finding of Aichi virus in clinical specimens from Germany and Brazil. The nucleotide sequences of both a German and a Brazilian isolate were determined, analyzed, and compared to known Aichi sequences. The German strain turned out to be a member of genogroup A, while the Brazilian belonged to genogroup B. For a primary assessment of the epidemiological importance of Aichi virus in Germany, a panel of 485 German serum samples was screened for antibody to Aichi virus, and a seroprevalence of 76% was found.