Use of Corynebacterium pseudodiphtheriticum for elimination of Staphylococcus aureus from the nasal cavity in volunteers exposed to abnormal microclimate and altered gaseous environment
Use of Corynebacterium pseudodiphtheriticum for elimination of Staphylococcus aureus from the nasal cavity in volunteers exposed to abnormal microclimate and altered gaseous environment
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DOI：
10.1007/s12602-013-9147-x
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发表时间：
2013-12-01
影响因子：
4.9
通讯作者：
Ilyin, V. K.
中科院分区：
文献类型：
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作者：
Kiryukhina, N. V.;Melnikov, V. G.;Ilyin, V. K.
在为期 30 天的室内实验中评估了含有假白喉杆菌盐悬浮液喷雾剂的有效性，该实验模拟了高温和污染空气对人体的影响。喷雾的目的是消除人类鼻腔中的金黄色葡萄球菌。在实验过程中，四名志愿者中有三名成为金黄色葡萄球菌携带者，其中一名是耐甲氧西林金黄色葡萄球菌（MRSA）的慢性携带者。喷雾应用根除了三名受试者的金黄色葡萄球菌，并减少了其在 MRSA 携带者中的存在。研究结果表明，假白喉杆菌可用于控制鼻腔环境中的金黄色葡萄球菌。不过，还需要进一步调查。
Effectiveness of saline suspension of Corynebacterium pseudodiphtheriticum containing spray was assessed in a 30-days chamber experiment modeling the effects of hyperthermia and polluted air on humans. Spray was targeted at eliminating Staphylococcus aureus from the nasal cavity of human subjects. Three of four volunteers became S. aureus carriers in the course of the experiment, and one was a chronic carrier of methicillin-resistant S. aureus (MRSA). Spray application eradicated S. aureus in three subjects and reduced its presence in the MRSA carrier. Results of the study suggest that C. pseudodiphtheriticum can be used for control of S. aureus in the nasal environment. However, further investigations are required.