The use of rapid-rate transcranial magnetic stimulation (rTMS) in refractory depressed patients
The use of rapid-rate transcranial magnetic stimulation (rTMS) in refractory depressed patients
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DOI：
10.1176/jnp.10.1.20
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发表时间：
1998-12-01
影响因子：
2.9
通讯作者：
Glover, S
中科院分区：
文献类型：
--
作者：
Figiel, GS;Epstein, C;Glover, S
快速经颅磁刺激(RTMS)允许对大脑皮层进行非侵入性检查。最近的研究已经开始调查rTMS是否对抑郁症有治疗作用。在本研究中，作者报道了rTMS治疗50例难治性抑郁症的安全性和有效性。总体而言，有21名应答者(42%)。有趣的是，56%的年轻患者对rTMS有反应。总体而言，所有患者对rTMS的耐受性良好。具体地说，在rTMS期间，没有患者出现新的癫痫发作。作者讨论了关于rTMS治疗抑郁症的现有文献以及未来的研究领域。
Rapid-rate transcranial magnetic stimulation (rTMS) allows for the noninvasive examination of the cerebral cortex. Recent studies have begun to investigate whether rTMS may be therapeutic for the treatment of depression. In the present study, the authors report on the safety and efficacy of rTMS in treating 50 patients with refractory depression. Overall, there were 21 responders (42%). Interestingly, 56% of the young patients responded to rTMS. Overall, rTMS was well tolerated in all patients. Specifically, no patient developed a new onset of seizures during rTMS. The authors discuss the extant literature on rTMS for the treatment of depression along with future areas of research.