An in vivo trial comparing the use of different types of 532 nm Nd:YAG lasers in the treatment of facial lentigines in Oriental patients
An in vivo trial comparing the use of different types of 532 nm Nd:YAG lasers in the treatment of facial lentigines in Oriental patients
复制标题
DOI：
10.1046/j.1524-4725.2000.00039.x
复制
发表时间：
2000-08-01
影响因子：
2.4
通讯作者：
Kono, T
中科院分区：
文献类型：
--
作者：
Chan, HH;Fung, WKK;Kono, T
背景Versapulse是一种由四种激光模式组成的系统，旨在提高成本效益。然而，由于这些激光器共享一个共同的电源，Q开关（QS）Nd：YAG 532 nm激光器的大光斑直径是必要的，以降低通量到一个合适的水平。这可能会增加色素沉着过度的风险，当用于治疗深色皮肤患者的雀斑。本研究的目的是评估Versapulse QS Nd：YAG 532 nm激光、Versapulse长脉冲Nd：YAG 532 nm激光（无冷却头）和传统QS Nd：YAG 532 nm激光治疗中国患者雀斑的临床疗效和并发症发生率。34名中国雀斑患者随机接受激光手术，一侧面部接受一种激光治疗，另一侧接受不同的系统治疗。监测患者6周，以评估透明、色素沉着过度、色素减退和红斑的程度。评估涉及使用视觉模拟问卷和两个盲观察员谁评价治疗前和治疗后的临床症状进行了采访的患者。Versapulse QS Nd：YAG 532 nm激光与统计学上更高的并发症风险相关。在临床疗效和并发症发生率方面，Versapulse长脉冲Nd：YAG 532 nm激光与传统QS Nd：YAG 532 nm激光兼容。Versapulse长脉冲532 nm激光更有效，应替代Versapulse QS Nd：YAG 532 nm激光治疗深色皮肤患者的雀斑。
BACKGROUND. Versapulse is a system that consists of four laser modalities and was developed with the aim of increasing cost-effectiveness. However, as these lasers share a common power supply, for the Q-switched (QS) Nd:YAG 532 nm laser a large spot diameter is necessary to lower the fluence to a suitable level. This can increase the risk of hyperpigmentation when used for the treatment of lentigines in dark-skinned patients.OBJECTIVE. The aim of our study was to access the clinical efficacy and the complication rate of the Versapulse QS Nd:YAG 532 nm laser, the Versapulse long-pulsed Nd:YAG 532 nm laser (without the chill tip), and a conventional QS Nd:YAG 532 nm laser in the treatment of lentigines in Chinese patients.METHODS. Thirty-four Chinese patients with lentigines were randomized to receive laser surgery, with one side of the face treated by one laser and the other side treated by a different system. Patients were monitored for 6 weeks to assess the degree of clearing, hyperpigmentation, hypopigmentation, and erythema. Assessments involved patients interviewed using a visual analog questionnaire and two blinded observers who evaluated the pre- and posttreatment clinical photographs.RESULTS. The Versapulse QS Nd:YAG 532 nm laser was associated with a statistically higher risk of complications. The Versapulse long-pulsed Nd:YAG 532 nm laser was compatible with the conventional QS Nd:YAG 532 nm laser in terms of clinical efficacy and complication rates.CONCLUSION. The Versapulse long-pulsed 532 nm laser is more effective and should be used instead of the Versapulse QS Nd:YAG 532 nm laser for the treatment of lentigines in dark-skinned patients.