Dialysis or transplantation?

Dialysis or transplantation?
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透析还是移植?

DOI:
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发表时间:
1983
期刊:
Journal of the American Medical Association (JAMA)
影响因子:
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通讯作者:
C. Blagg
C. Blagg
中科院分区:
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文献类型:
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作者:
C. Blagg

文献摘要

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肾脏病学家普遍认为,成功的移植是许多终末期肾病(ESRD)患者的最佳治疗方法。因此,Terasaki等在本期杂志上发表的文章(第1065页)描述了近年来移植前输血的移植结果的改善,这是一个重要的问题。然而,在评估移植在治疗终末期肾病中的作用时,必须解决几个问题。这些因素包括能够实际接受移植的患者数量、手术的有效性、患者对这种治疗方式的偏好以及成本。有多少接受透析的患者实际上是移植的候选人?现在开始透析的患者的平均年龄是50多岁,但许多人认为这是移植的年龄上限。1因此,在美国接受透析的新患者中,约有一半年龄过大,无法进行移植。
Nephrologists are in general agreement that a successful transplant is the optimal treatment for many patients with end-stage renal disease (ESRD). Therefore, the article in this issue ofThe Journalby Terasaki et al (p 1065) describing the improved results of transplantation in recent years with pretransplant blood transfusions is an important one. Nevertheless, in assessing the role of transplantation in the treatment of ESRD, several questions must be addressed. These include the number of patients that can realistically receive transplants, the effectiveness of the procedure, the patient preference for this treatment modality, and the cost. How many patients undergoing dialysis are, in fact, candidates for transplantation? The mean age of patients starting dialysis is now in the middle 50s, yet many consider this to be the upper age limit for transplantation. 1 Therefore, about half the new patients undergoing dialysis in the United States are too old for transplantation.