Spatial programming of gene expression in early Drosophila embryogenesis.

Spatial programming of gene expression in early Drosophila embryogenesis.
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果蝇早期胚胎发生中基因表达的空间编程。

DOI:
10.1146/annurev.cb.02.110186.000405
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发表时间:
1986
期刊:
Annual review of cell biology
影响因子:
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通讯作者:
O'Farrell,PH
O'Farrell,PH
中科院分区:
--
文献类型:
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作者:
Scott,MP;O'Farrell,PH

文献摘要

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发育生物学最基本的问题之一是空间模式是如何产生的。果蝇基因表达研究的最新进展为基因控制模式的机制提供了线索。已经发现调节果蝇胚胎发育的基因以不同的空间模式表达,这些空间模式先于胚胎中形态模式的出现并使其成为可能。因此,图案形成的问题可以表述为:
One of the most fundamental issues of developmental biology is how spatial patterns are generated. Recent developments in the study of gene expression in Drosophila have provided clues to the mechanisms whereby genes control pattern. Genes that regulate Drosophila embryonic development have been found to be expressed in distinct spatial patterns that precede and make possible the appearance of morphological patterns in the embryo. Therefore, the problem of pattern formation can be stated as