Effect of maternal caffeine consumption on heart rate and sleep time of breast-fed infants.

Effect of maternal caffeine consumption on heart rate and sleep time of breast-fed infants.
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母亲咖啡因摄入量对母乳喂养婴儿心率和睡眠时间的影响。

DOI:
10.1159/000457060
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发表时间:
1985
期刊:
Developmental pharmacology and therapeutics
影响因子:
--
通讯作者:
Ryu,JE
Ryu,JE
中科院分区:
--
文献类型:
--
作者:
Ryu,JE

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研究人员对 11 对母婴进行了研究,以确定母亲摄入咖啡因(500 毫克/天)对婴儿心率和睡眠时间的影响。在平衡交叉设计中,母亲在一个 5 天期间每天摄入 5 杯脱咖啡因咖啡,并在另外 5 天期间每天摄入 5 杯添加咖啡因的脱咖啡因咖啡(100 mμ/杯)。在咖啡因期的最后一天,牛奶中咖啡因的浓度范围为1.6至6.2微克/毫升,婴儿的咖啡因摄入量估计为0.3-1.0毫克/公斤/天。在任一实验期的最后一天,婴儿血清均未检测到咖啡因含量。咖啡因和无咖啡因期间的表现在 24 小时心率或睡眠时间方面没有显着差异。
Eleven mother-infant pairs were studied to determine the effect of maternal caffeine ingestion (500 mg/day) on heart rate and sleep time of the infants. In a balanced cross-over design, mothers ingested 5 cups of decaffeinated coffee daily during one 5-day period and 5 cups of decaffeinated coffee with added caffeine (100 mµ/cup) during another 5-day period. Concentrations of caffeine in milk on the last day of the caffeine period ranged from 1.6 to 6.2 µg/ml and the intake of caffeine by the infants was estimated to be 0.3-1.0 mg/kg/day. Infant serum did not contain detectable amounts of caffeine on the last day of either experimental period. Performance during the caffeine and no-caffeine periods was not significantly different with respect to either 24-hour heart rate or sleep time.