Cyclic variation of integrated ultrasound backscatter in the left ventricle during the early neonatal period
Cyclic variation of integrated ultrasound backscatter in the left ventricle during the early neonatal period
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DOI：
10.1067/mhj.2000.108515
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发表时间：
2000-09-01
影响因子：
4.8
通讯作者：
Kitahata, H
中科院分区：
文献类型：
--
作者：
Mori, K;Manabe, T;Kitahata, H
背景新生儿早期心室肌的收缩力和组织学结构发生显着变化。超声背向散射积分（IBS）的周期性变化（CV）反映了心肌的收缩性能。本研究的目的是定义正常值及其系列变化的CV IBS在左ventricular of normal newborns.Methods and Results我们记录了长轴IBS图像在169名健康新生儿出生后14天内（平均4.6 +/- 4.2天），并在84名婴儿和儿童（平均年龄8.7 +/- 5.2岁）。对于每一个，我们得到了CV的IBS在室间隔（CVIVS）和后壁（CVPW）在新生儿，有一个显着的线性相关性CV和出生后的日期在测量室间隔和后壁（r = 0.57和0.60，分别）。在婴幼儿和儿童中，年龄与CVIVS或CVPW无显著关系。在出生后>4天的新生儿中，CVIVS的幅度与婴儿或儿童无显著差异。出生后>9天的新生儿CVPW仍明显低于婴儿和儿童（P <0.005）。新生儿CVIVS/CVPW比值（0.99 ± 0.29vs0.80 ± 0.22，P <0.001）明显高于婴儿和儿童。CVIVS/CVPW的高值可能反映了胎儿期右心室相对高收缩性能的残留。
Background Significant changes in the contractility and histologic structure of the ventricular myocardium occur during the early neonatal period. Cyclic variation (CV) of ultrasonic integrated backscatter (IBS) reflects myocardial contractile performance. The aim of this study was to define normal values of and its serial changes in CV of IBS in the left ventricle of normal neonates.Methods and Results We recorded long-axis IBS images in 169 healthy neonates within 14 days after birth (mean 4.6 +/- 4.2 days) and in 84 infants and children (mean age 8.7 +/- 5.2 years). For each, we obtained CV of IBS in the interventricular septum (CVIVS) and the posterior wall (CVPW) In neonates, there was a significant linear correlation between CV and date after birth in measurements of both the interventricular septum and the posterior wall (r = 0.57 and 0.60, respectively). in infants and children, there was no significant relation between age and CVIVS or CVPW. In neonates >4 days after birth, the magnitude of CVIVS was not significantly different from that in infants or children. By contrast, the magnitude of CVPW was still significantly decreased in neonates >9 days after birth compared with that in infants and children (P < .005). The ratio of CVIVS to CVPW (CVIVS/CVPW) was significantly higher in neonates than in infants and children (0.99 +/- 0.29 vs 0.80 +/- 0.22, P < .001).Conclusions Both CVIVS and CVPW in neonates gradually increase after birth, indicating developmental maturation of the left ventricle. High valves of CVIVS/CVPW might reflect the remnant of relatively high contractile performance in the right ventricle during fetal life.