Value of computed tomography in interstitial 125I brachytherapy of prostatic carcinoma.
Value of computed tomography in interstitial 125I brachytherapy of prostatic carcinoma.
复制标题
CT在前列腺癌间质125I近距离放射治疗中的价值
DOI：
10.1148/radiology.146.2.6849093
复制
发表时间：
1983
期刊：
影响因子：
19.7
通讯作者：
A. Moss
中科院分区：
文献类型：
--
作者：
R. Gore;A. Moss
对20例局限性前列腺癌患者进行了125I粒子组织间植入前后的CT检查。扫描分析以确定前列腺体积、种子位置、肿瘤反应和前列腺周肿瘤扩散。CT体积平均比临床估计高出25%-30%。此外，CT发现17例(85%)植入错误，包括分布不均匀和前列腺外种子。植入后的连续扫描显示，12名患者(60%)的前列腺体积没有变化，7名患者(35%)的前列腺体积减少，1名患者(5%)的前列腺体积增加，这与临床对治疗反应的评估一致。在2例患者中，在CT扫描上发现临床上未怀疑的肿瘤扩散。
Computed tomography (CT) was performed in 20 patients with localized prostatic carcinoma before and after interstitial implantation of 125I seeds. Scans were analyzed to determine prostate volume, seed location, tumor response, and periprostatic tumor spread. CT volumes were an average of 25-30% greater than clinical estimates. In addition, CT demonstrated errors in implantation, including inhomogeneous distribution and extraprostatic seeds, in 17 patients (85%). Serial post-implantation scans showed no change in prostate volume in 12 patients (60%), a decrease in 7 (35%), and an increase in 1 (5%), concurring with clinical assessment of response to therapy. In 2 patients, clinically unsuspected tumor spread was identified on the CT scan.