Animal models of Helicobacter pylori infection and disease
Animal models of Helicobacter pylori infection and disease
复制标题
DOI：
10.1016/s1286-4579(03)00123-0
复制
发表时间：
2003-07-01
影响因子：
5.8
通讯作者：
Lee, A
中科院分区：
文献类型：
--
作者：
O'Rourke, JL;Lee, A
幽门螺杆菌被认为是一种主要的人类病原体，因此有必要开发动物模型，以帮助阐明这种细菌的致病机制，并帮助制定改进的胃病治疗策略。已经开发出利用一系列动物物种的适当模型来检查诸如宿主反应和细菌因素对疾病发展的影响以及新治疗方案（包括疫苗接种）是否成功治愈感染等因素。 (C) 2003 年科学与医学版 Elsevier SAS。版权所有。
The acceptance of Helicobacter pylori as a major human pathogen has necessitated the development of animal models to help elucidate the pathogenic mechanisms of this bacterium and aid in the development of improved strategies for the treatment of gastric disease. Appropriate models, utilising a range of animal species, have been developed to examine factors such as the influence of host responses and bacterial factors in disease development and the success of new therapeutic regimens, including vaccination, to cure infection. (C) 2003 Editions scientifiques et medicales Elsevier SAS. All rights reserved.