Asbestos lung fibre concentrations in South African chrysotile mine workers.
Asbestos lung fibre concentrations in South African chrysotile mine workers.
复制标题
南非温石棉矿工的石棉肺纤维浓度。
DOI：
10.1093/annhyg/45.6.473
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发表时间：
2001
影响因子：
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通讯作者：
Fred Pooley
中科院分区：
文献类型：
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作者：
David Rees;James I. Phillips;E. Garton;Fred Pooley
间皮瘤还没有发现在南非温石棉矿工和米莱尔，尽管几十年来每年生产约10万吨的矿物。对这种癌症的稀少或不存在的一种可能的解释可能是相对缺乏污染的纤维透闪石，一种与温石棉矿石共生的角闪石。用透射电镜观察了9名温石棉矿工人肺纤维含量。尽管在大多数情况下使用了相当长的时间（中位数为9.5年;范围为32-4年），但温石棉纤维的浓度相对较低：只有两个案例超过114万纤维/克干肺。透闪石纤维水平甚至更低：除一个病例外，所有病例均低于100万纤维/克干燥肺。仅在两种情况下，透闪石纤维浓度超过温石棉。这些结果支持了南非温石棉并未受到透闪石严重污染的论点。
Mesothelioma has not been found in South African chrysotile miners and millers despite decades of producing about 100000 tons of the mineral per year. One possible explanation for the scarcity or absence of the cancer may be a relative lack of contaminating fibrous tremolite, an amphibole that variably occurs with chrysotile ores. The fibre content in the lungs of nine former chrysotile mine workers was ascertained by transmission electron microscopy. Despite fairly long service in most cases (median 9.5 yr; range 32-4 yr) the concentrations of chrysotile fibres were relatively low: only two cases exceeded 1.14 million fibres/g dried lung. Tremolite fibre levels were even lower: less than 1 million fibres/g dried lung in all but one case. Tremolite fibre concentrations exceeded those of chrysotile in only two cases. These results support the contention that South African chrysotile is not heavily contaminated by tremolite.