ANTIMICROBIAL ACTIVITIES OF CRUDE LEAF EXTRACTS OF ACALYPHA-WILKESIANA

ANTIMICROBIAL ACTIVITIES OF CRUDE LEAF EXTRACTS OF ACALYPHA-WILKESIANA
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DOI:
10.1016/0378-8741(93)90033-2
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发表时间:
1993-08-01
影响因子:
5.4
通讯作者:
IROBI, ON
IROBI, ON
中科院分区:
医学2区
文献类型:
--
作者:
ALADE, PI;IROBI, ON

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通过琼脂扩散和管稀释技术研究了铁苋菜叶的水、乙醇、氯仿和己烷提取物的体外抗菌活性。水和乙醇提取物抑制标准和当地细菌和真菌菌株的生长,包括金黄色葡萄球菌、红色毛癣菌、须癣毛癣菌、白色念珠菌和黄曲霉。水提取物对肺炎克雷伯菌和奇异变形杆菌没有任何抑制作用,而乙醇提取物则有活性。提取物的最低抑制浓度在0.25至32mg/ml之间,而最低杀灭浓度在1.0至64mg/ml之间。发现水提取物具有静态作用,而乙醇提取物具有均匀的杀灭作用。
Water, ethanol, chloroform and hexane extracts of Acalypha wilkesiana leaves were investigated for in vitro antimicrobial activities by agar-diffusion and tube-dilution techniques. The water and ethanol extracts inhibited the growth of standard and local strains of bacteria and fungi including Staphylococcus aureus, Trichophyton rubrum, Trichophyton mentagrophytes, Candida albicans and Aspergillus flavus. The aqueous extract did not exert any inhibitory action on Klebsiella pneumoniae and Proteus mirabilis while the ethanol extract was active. The minimum inhibitory concentrations of the extracts ranged between 0.25 and 32 mg/ml, while the minimum cidal concentrations were between 1.0 and 64 mg/ml. The aqueous extract was found to be static in action while the ethanolic extract was uniformly cidal in effect.