Histological Characteristics of Extracted Hydroxyapatite-coated Implants
Histological Characteristics of Extracted Hydroxyapatite-coated Implants
复制标题
提取的羟基磷灰石涂层植入物的组织学特征
DOI：
10.2186/prp.3.69
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发表时间：
2004
期刊：
影响因子：
--
通讯作者：
M. Morito
中科院分区：
文献类型：
--
作者：
H. Oguchi;Yasuyo Karube;M. Morito
目的：本研究的目的是对临床应用后的牙髓骨内种植体的羟基磷灰石（HA）涂层进行组织学检查。使用高速火焰喷涂技术 (HVFST) 应用 HA。 材料和方法：对六年前在两名不同患者体内植入的两个植入物进行了研究。第一位患者是一名 24 岁男性，在切除根囊肿后接受种植治疗以改善冠根比。第二名患者是一名 15 岁男孩，他在牙根折断后植入了种植体以恢复牙列。将提取的材料固定在10%福尔马林溶液中，并用光学显微镜和扫描电子显微镜（SEM）检查。结果：由于种植体与骨紧密粘附，因此需要去除种植体和周围的骨。在 SEM 中使用甲苯胺蓝染色进行的组织学检查表明，一些剩余的 HA 涂层直接接触了第一位患者的骨骼。在第二名患者中，SEM 显示 HA 涂层已被吸收，并且骨头已直接与钛结合。结论：虽然每个种植体已使用六年，但涂层 HA 层显示出完全不同的现象。我们得出的结论是，造成这种差异的原因与HA涂层技术的局限性和各种长期临床条件有关。
Purpose : The purpose of this study was to histologically examine the hydroxyapatite (HA)-coated layer of endodontic endosseous implants after clinical application. The HA was applied using a high-velocity flame-spraying technique (HVFST).Materials and Methods : Two implants placed six years earlier in two different patients were studied. The first patient was a 24-year-old man who received implant therapy to improve the crown : root ratio after removal of a radicular cyst. The second patient was a 15-year-old boy in whom an implant was placed to restore the dentition after dental root breakage. The extracted materials were fixed in a 10% formalin solution and examined with light microscopy and scanning electron microscopy (SEM).Results : Because the implants adhered tightly to the bone, it was necessary to remove both the implant and the surrounding bone. Histological examination using toluidine blue staining in an SEM indicated some remaining HA coating that directly contacted the bone in the first patient. In the second patient, SEM showed that the HA coating had been resorbed, and the bone had bound directly to the titanium.Conclusion : Although each of the implants had been in use for six years, the coated HA layers displayed completely different phenomena. We concluded that the causes for this difference were related to the limitations of the HA coating technique and various long-term clinical conditions.