INCIDENCE AND PROGNOSIS OF SUBARACHNOID HEMORRHAGE IN A JAPANESE RURAL-COMMUNITY

INCIDENCE AND PROGNOSIS OF SUBARACHNOID HEMORRHAGE IN A JAPANESE RURAL-COMMUNITY
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DOI:
10.1161/01.str.20.9.1150
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发表时间:
1989-09-01
期刊:
影响因子:
8.3
通讯作者:
FUJISHIMA, M
FUJISHIMA, M
中科院分区:
医学1区
文献类型:
--
作者:
KIYOHARA, Y;UEDA, K;FUJISHIMA, M

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在1,621名年龄≥的Hisayama居民中发生了26例首次蛛网膜下腔出血。前瞻性研究22年随访期间的40年。蛛网膜下腔出血是由临床和尸检结果证实。年平均发病率(96.1/100 000人口)比以往报告的任何发病率高出3-13倍,而且随着年龄的增长,男女发病率都急剧上升,在调整年龄后,妇女的发病率是男子的2.3倍。9例患者(35%)死亡。蛛网膜下腔出血发作后8小时。没有一个在死亡证明上被正确诊断,9个中的4个(44%)被误诊为脑出血。我们发现蛛网膜下腔出血患者的存活率远低于以前的报道,因为我们通过我们队列中的高尸检率(81.4%)发现了大量因蛛网膜下腔出血而猝死的患者。
Twenty-six first episodes of subarachnoid hemorrhage occurred among 1,621 Hisayama residents aged .gtoreq. 40 years during the 22-year follow-up of a prospective study. Subarachnoid hemorrhage was confirmed by both clinical and autopsy findings. The average annual incidence (96.1/100,000 population) was 3-13 times higher than any previously reported and steeply increased with age in both sexes, being 2.3 times higher for women than for men after adjusting for age. Nine patients (35%) died .ltoreq. 8 hours after the onset of subarachnoid hemorrhage. None was correctly diagnosed on the death certificates, and four of the nine (44%) were misdiagnosed as intracerebral hemorrhage. We found the survival rate of patients suffering subarachnoid hemorrhage to be much lower than previously reported because we detected a large number of sudden deaths due to subarachnoid hemorrhage through the high rate of autopsy in our cohort (81.4%).