In vivo and in vitro antimicrobial activity of Azadirachta indica (Lin) against Citrobacter freundii isolated from naturally infected Tilapia (Oreochromis mossambicus)
In vivo and in vitro antimicrobial activity of Azadirachta indica (Lin) against Citrobacter freundii isolated from naturally infected Tilapia (Oreochromis mossambicus)
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DOI：
10.1016/j.aquaculture.2014.12.008
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发表时间：
2015-02
期刊：
影响因子：
4.5
通讯作者：
S. Thanigaivel;S. Vijayakumar;S. Gopinath;A. Mukherjee;N. Chandrasekaran;John Thomas
中科院分区：
文献类型：
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作者：
S. Thanigaivel;S. Vijayakumar;S. Gopinath;A. Mukherjee;N. Chandrasekaran;John Thomas
水产品健康管理要求通过稳定经济损失和实施各种天然植物生物产品来治疗病原菌，从而实现生产的持续增长。从某养鱼场采集的罗非鱼鱼种中分离到的弗氏柠檬酸杆菌，其致病作用表现为尾部坏死、败血症、出血和身体变红等症状。C. Freundii对各种药用植物进行了测试。在筛选的3种植物中，印楝（Azadirachta indica，Neem）对炭疽病菌具有较好的抑菌活性。本研究表明A.在体内浓度为150毫克/升的indicaplant提取物可用作抗生素的替代物来治疗这种细菌感染。使用药用植物提取物介导的治疗被认为是非常有效的控制这种细菌感染。
Aquaculture health management demands a constant growth in the production by stabilizing economic loss and implementing various natural plant-based bio products for treating pathogenic bacteria. Pathogenic effects of theCitrobacter freundiiisolated from fingerlings of Tilapia collected from a fish farm showed symptoms like tail necrosis, septicemia, hemorrhage, and reddening of the body. Antibacterial activity ofC. freundiiwas tested against various medicinal plants. Of the three plants screened,Azadirachta indica(Neem) showed good antibacterial activity againstC. freundii.The present study revealed thatA. indicaplant extract at a concentration of 150 mg/l in vivo can be used as an alternative to antibiotics for treating this bacterial infection. The use of medicinal plant extract-mediated treatment was found to be very effective in controlling this bacterial infection.