Computer Therapy Compared With Usual Care for People With Long-Standing Aphasia Poststroke A Pilot Randomized Controlled Trial
Computer Therapy Compared With Usual Care for People With Long-Standing Aphasia Poststroke A Pilot Randomized Controlled Trial
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DOI：
10.1161/strokeaha.112.650671
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发表时间：
2012-07-01
期刊：
影响因子：
8.3
通讯作者：
Hughes, Helen
中科院分区：
文献类型：
--
作者：
Palmer, Rebecca;Enderby, Pam;Hughes, Helen
背景和目的-本研究的目的是测试进行随机对照试验的可行性，研究自我管理的计算机治疗的有效性与长期失语症中风后的人。方法-在这个试点单盲，平行组，随机对照试验参与者失语症被分配到自我管理的计算机治疗与志愿者的支持或日常护理（日常语言活动）。5个月的干预期后3个月没有干预调查treatmentmaintenance.Results-Thirty-four参与者被招募。每组分配17名参与者。13名来自常规护理组的参与者和15名来自计算机治疗组的参与者在5个月时进行了随访。平均4小时43分钟的演讲和语言治疗时间和4小时的志愿者支持时间，使平均25小时的独立实践。5个月时，两组间命名能力较基线的百分比变化差异为19.8%（95% CI，4.4-35.2; P=0.014），治疗组更优。患有更严重失语症的参与者几乎没有受益。结果表明早期迹象的成本效益的自我管理的计算机therapy.Conclusion-This试点试验表明，自我管理的计算机治疗失语症是可行的，这将是切实可行的招募足够的参与者进行适当的动力临床试验，调查自我管理的计算机治疗的有效性，为长期失语症的人临床试验注册-www.controlled-trials.com.唯一标识符：ISRCTN 91534629。（中风。2012;43：1904-1911.）
Background and Purpose-The purpose of this study was to test the feasibility of conducting a randomized controlled trial to study the effectiveness of self-managed computer treatment for people with long-standing aphasia after stroke.Method-In this pilot single-blinded, parallel-group, randomized controlled trial participants with aphasia were allocated to self-managed computer treatment with volunteer support or usual care (everyday language activity). The 5-month intervention period was followed by 3 months without intervention to investigate treatment maintenance.Results-Thirty-four participants were recruited. Seventeen participants were allocated to each group. Thirteen participants from the usual care group and 15 from the computer treatment group were followed up at 5 months. An average of 4 hours 43 minutes speech and language therapy time and 4 hours volunteer support time enabled an average of 25 hours of independent practice. The difference in percentage change in naming ability from baseline at 5 months between groups was 19.8% (95% CI, 4.4-35.2; P=0.014) in favor of the treatment group. Participants with more severe aphasia showed little benefit. Results demonstrate early indications of cost-effectiveness of self-managed computer therapy.Conclusion-This pilot trial indicates that self-managed computer therapy for aphasia is feasible and that it will be practical to recruit sufficient participants to conduct an appropriately powered clinical trial to investigate the effectiveness of self-managed computer therapy for people with long-standing aphasia.Clinical Trial Registration-www.controlled-trials.com. Unique identifier: ISRCTN91534629. (Stroke. 2012;43:1904-1911.)