Choosing a control group in effectiveness trials of behavioral drug abuse treatments

Choosing a control group in effectiveness trials of behavioral drug abuse treatments
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DOI:
10.1016/j.jsat.2009.05.004
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发表时间:
2009-12-01
影响因子:
3.9
通讯作者:
Dempsey, Catherine L.
Dempsey, Catherine L.
中科院分区:
医学2区
文献类型:
--
作者:
Brigham, Gregory S.;Feaster, Daniel J.;Dempsey, Catherine L.

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有效性试验是开发和评估行为治疗的科学过程中的重要一步。与疗效研究相比,对疗效研究的关注对研究设计提出了一套不同的要求。控制条件的选择对临床试验的内部和外部有效性有许多影响。本文的目的是提供一个讨论的问题,选择一个控制组的有效性试验的行为干预药物滥用治疗。作者描述了四种试验设计,并讨论了每种设计的优缺点。(C)2009 Elsevier Inc. All rights reserved.
Effectiveness trials are an important step in the scientific process of developing and evaluating behavioral treatments. The focus on effectiveness research presents a different set of requirements on the research design when compared with efficacy studies. The choice of a control condition has many implications for a clinical trial's internal and external validity. The purpose of this article was to provide a discussion of the issues involved in choosing a control group for effectiveness trials of behavioral interventions in substance abuse treatment. The authors provide a description of four trial designs and a discussion of the advantages and disadvantages of each. (C) 2009 Elsevier Inc. All rights reserved.