THE PHYSICAL PROPERTIES OF CYTOPLASM - A STUDY BY MEANS OF THE MAGNETIC PARTICLE METHOD .1. EXPERIMENTAL
THE PHYSICAL PROPERTIES OF CYTOPLASM - A STUDY BY MEANS OF THE MAGNETIC PARTICLE METHOD .1. EXPERIMENTAL
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DOI：
10.1016/0014-4827(50)90048-6
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发表时间：
1950-01-01
影响因子：
3.7
通讯作者：
HUGHES, AFW
中科院分区：
文献类型：
--
作者：
CRICK, FHC;HUGHES, AFW
描述了一种方法。用于研究组织培养物中细胞质的一致性。磁性颗粒被细胞吞噬；这些颗粒在外部磁场的作用下在细胞内旋转，它们的位移被电影显微镜记录下来。研究表明，鸡胚成骨细胞的细胞质是一种弱弹性流体，其刚性模量约为102达因/厘米2。有触变行为的证据。这些结果不支持假设纤维胶束交错网络的原生质结构理论。这表明这些细胞的细胞质的精细结构更加多样化和不稳定。
A method is descr. for the study of the consistency of the cytoplasm of cells in the outgrowth of tissue cultures. Magnetic particles are phagocytosed by the cells; these particles are rotated within the cell by an external magnetic field, and their displacement is recorded by the cine-microscope. It has been shown that the cytoplasm of chick embryonic osteoblasts is a weakly elastic fluid, with a modulus of rigidity of the order of 102 dynes/cm2. There is evidence of thixotropic behavior. These results do not support theories of protoplasmic structure which postulate an interlacing network of fibrous micelles. It is suggested that the fine structure of the cytoplasm of these cells is much more varied and labile.