Relationships between Insecticidal Activity of 6-Alkylthio-2-pyridyl Methanesulfonates and Acetyicholinesterase Inhibition of their Sulfone Derivatives against Nephotettix eincticeps
Relationships between Insecticidal Activity of 6-Alkylthio-2-pyridyl Methanesulfonates and Acetyicholinesterase Inhibition of their Sulfone Derivatives against Nephotettix eincticeps
复制标题
6-烷硫基-2-吡啶基甲磺酸盐杀虫活性与其砜衍生物对黑尾叶蝉乙酰胆碱酯酶抑制作用的关系
DOI：
10.1584/jpestics.15.63
复制
发表时间：
2010
期刊：
影响因子：
--
通讯作者：
Shuichi Ishida Ageo
中科院分区：
文献类型：
--
作者：
Masuko Kosayashi;Akio Masui;Shuichi Ishida Ageo
测定了15个6-烷硫基-2-吡啶基甲烷磺酸盐的磺化类似物对尖头小蜂乙酰胆碱酯酶制剂的抑制活性(I50)。当分子的疏水性因子(Logh)可能参与运输时，6-烷基硫代衍生物对两个菌株的杀虫活性与相应的砜的乙酰胆碱酯酶抑制活性高度相关。
The inhibitory activity (I50) of fifteen sulfone analogs of 6-alkylthio-2-pyridyl methanesulfonates was measured against acetylcholinesterase preparations from Ageo and Izumi strains of Nephotettix cincticeps. The insecticidal activity of 6-alkylthio derivatives to both strains was highly related to the acetylcholinesterase-inhibitory activity of the corresponding sulfones when hydrophobicity factors (log h) of the molecule perhaps participating in the transport