Screening for HIV infection in high-risk communities by urine antibody testing

Screening for HIV infection in high-risk communities by urine antibody testing
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DOI:
10.1097/00126334-200212010-00008
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发表时间:
2002-12-01
影响因子:
3.6
通讯作者:
Nelson, KE
Nelson, KE
中科院分区:
医学3区
文献类型:
--
作者:
Hilton, C;Sabundayo, BP;Nelson, KE

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目的:为了评估尿液筛查检测HIV感染者在高流行率community.Methods的有效性:尿液HIV检测进行了16个离散的事件和4个正在进行的测试站点在巴尔的摩社区的HIV感染的高发病率。如果可能,通过血液检测确认尿液检测结果阳性。此外,我们试图从受试者谁报告可能暴露于HIV,但没有一个阳性的尿液test.Results:从1998年2月至2001年8月,我们筛选了1718人的血液样本。总体而言,210人(12%)是艾滋病毒阳性,其中169人(80%)以前从未检测呈阳性; 87%的那些谁检测呈阳性收到他们的结果,大多数被转介到medicalcare.Conclusions:尿液为基础的艾滋病毒感染筛查在高流行率的内城社区可以是一个有效的工具,用于识别和治疗感染者谁不知道他们的感染。
Objectives: To evaluate the effectiveness of urine screening to detect HIV-infected individuals in high-prevalence communities.Methods: Urine HIV testing was performed at 16 discrete events and four ongoing testing sites in Baltimore communities with a high incidence of HIV infection. When possible, positive urine test results were confirmed by blood testing. In addition, we attempted to obtain blood samples from subjects who reported a possible exposure to HIV but did not have a positive urine test.Results: From February 1998 to August 2001, we screened 1718 persons. Overall, 210 persons (12%) were HIV-positive, of whom 169 (80%) had never previously tested positive; 87% of those who tested positive received their results, and most were referred for medical care.Conclusions: Urine-based screening for HIV infection in high-prevalence inner city communities can be an effective tool for identifying and treating infected persons who are unaware of their infection.