Fewer non-COVID-19 respiratory tract infections and gastrointestinal infections during the COVID-19 pandemic
Fewer non-COVID-19 respiratory tract infections and gastrointestinal infections during the COVID-19 pandemic
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DOI：
10.1002/jmv.27321
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发表时间：
2021-09-12
影响因子：
12.7
通讯作者：
Kostev, Karel
中科院分区：
文献类型：
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作者：
Tanislav, Christian;Kostev, Karel
为防止2019冠状病毒病（COVID-19）大流行的传播，戴口罩、保持社交距离及手部卫生等措施发挥了关键作用。这些措施也可能影响到其他传染病的蔓延，如呼吸道感染和胃肠道感染。因此，我们旨在于COVID-19大流行期间调查非COVID-19相关RTI及GII。纳入了德国994名全科医生（GP）或192名儿科医生中匿名记录的诊断为急性RTI（不同部位）或急性GII的患者。我们比较了2019年4月至2020年3月和2020年4月至2021年3月期间急性RTI和GII的患病率。在全科医生的实践中，715，440名患者在非大流行期间被诊断为RTI或GII，而在大流行期间为468，753人;儿科医生也观察到了同样的趋势（275，033 vs. 165，127）。通过GP，观察到流感诊断的最大下降（-71%，p < 0.001），其次是急性喉炎（-64%，p < 0.001）、急性下呼吸道感染（支气管炎）（-62%，p < 0.001）和肠道感染（-40%，p < 0.001）。相比之下，相对罕见的病毒性肺炎大幅增加了229%（p < 0.001）。在儿科实践中，感染诊断大幅下降，尤其是流感（-90%，p < 0.001）、肺炎（-73%，p < 0.001病毒性肺炎;-76%，p < 0.001其他肺炎）和急性鼻窦炎（-66%，p < 0.001）。儿童病毒性肺炎未观察到增加。2019冠状病毒病大流行期间，为对抗SARS-CoV-2的传播而对社会生活实施了相当大的限制，这也导致了其他非2019冠状病毒病呼吸道和胃肠道感染的意外但可喜的减少。
For preventing the spread of the coronavirus disease 2019 (COVID-19) pandemic, measures like wearing masks, social distancing, and hand hygiene played crucial roles. These measures may also have affected the expansion of other infectious diseases like respiratory tract infections (RTI) and gastro-intestinal infections (GII). Therefore, we aimed to investigate non-COVID-19 related RTI and GII during the COVID-19 pandemic. Patients with a diagnosis of an acute RTI (different locations) or acute GII documented anonymously in 994 general practitioner (GP) or 192 pediatrician practices in Germany were included. We compared the prevalence of acute RTI and GII between April 2019-March 2020 and April 2020-March 2021. In GP practices, 715,440 patients were diagnosed with RTI or GII in the nonpandemic period versus 468,753 in the pandemic period; the same trend was observed by pediatricians (275,033 vs. 165,127). By GPs, the strongest decrease was observed for the diagnosis of influenza (-71%, p < 0.001), followed by acute laryngitis (-64%, p < 0.001), acute lower respiratory infections (bronchitis) (-62%, p < 0.001), and intestinal infections (-40%, p < 0.001). In contrast, the relatively rare viral pneumonia strongly increased by 229% (p < 0.001). In pediatrician practices, there was a strong decrease in infection diagnoses, especially influenza (-90%, p < 0.001), pneumonia (-73%, p < 0.001 viral; -76%, p < 0.001 other pneumonias), and acute sinusitis (-66%, p < 0.001). No increase was observed for viral pneumonia in children. The considerable limitations concerning social life implemented during the COVID-19 pandemic to combat the spread of SARS-CoV-2 also resulted in an inadvertent but welcome reduction in other non-Covid-19 respiratory tract and gastro-intestinal infections.