Perfluorocarbon enhancement of heterologous red cell survival: a reticuloendothelial block effect?
Perfluorocarbon enhancement of heterologous red cell survival: a reticuloendothelial block effect?
复制标题
全氟化碳增强异源红细胞存活：网状内皮阻滞效应？
DOI：
10.1159/000233279
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发表时间：
1983
期刊：
影响因子：
--
通讯作者：
Rowe,AW
中科院分区：
文献类型：
--
作者：
Castro,O;Reindorf,CA;Socha,WW;Rowe,AW
用全氟化碳红细胞替代物（Fluosol DA）输注受体，延长了输注给灵长类动物的人红细胞的血管内存活。这种效应可能是由于全氟化碳乳剂暂时阻断了动物的网状内皮系统。全氟碳化合物可用于研究网状内皮功能在红细胞免疫破坏中的作用。
The intravascular survival of human erythrocytes transfused to primate animals was prolonged by infusing the recepients with a perfluorocarbon red cell substitute (Fluosol DA). This effect is probably due to transient block of the animals’ reticuloendothelial system by the perfluorocarbon emulsion. Perfluorocarbon compounds could be used to study the role of reticuloendothelial function in the immune destruction of red cells.