Skin Disorders Associated with Obesity in Children and Adolescents: A Population- Based Study
Skin Disorders Associated with Obesity in Children and Adolescents: A Population- Based Study
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DOI：
10.1111/pde.12271
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发表时间：
2014-03-01
影响因子：
1.5
通讯作者：
Carpenter, Diane M.
中科院分区：
文献类型：
--
作者：
Mirmirani, Paradi;Carpenter, Diane M.
在美国，儿童肥胖是一个主要的公共卫生问题。本研究的目的是确定肥胖儿童和青少年中各种皮肤病的患病率，并比较肥胖受试者和体重指数(BMI)正常者皮肤科服务的使用情况。这是一项在北加州凯撒永久管理医疗系统进行的基于人群的回溯性研究。主要观察指标是三个体重组(正常、超重、肥胖)中与胰岛素抵抗、雄激素过剩、细菌感染、真菌感染、病毒感染、炎症、机械变化和其他皮肤状况(汗膜炎、多汗症)相关的皮肤病的相对风险以及皮肤科就诊次数。共有248,775名受试者参加了调查。双变量分析显示，肥胖者的胰岛素抵抗障碍、细菌感染、真菌感染、炎症性疾病、机械改变和其他皮肤疾病的比例高于BMI正常者(p
Obesity in children is a major public health concern in the United States. The objectives of the current study were to determine the prevalence of various groups of cutaneous disorders in obese children and adolescents and to compare the use of dermatology services in obese subjects with that those with a normal body mass index (BMI). This was a retrospective, population-based study at the Kaiser Permanente Northern California Managed Healthcare System. The main outcome measures were the relative risk of cutaneous disorders associated with insulin resistance, androgen excess, bacterial infection, fungal infection, viral infection, inflammation, mechanical changes, and other skin conditions (hidradenitis, hyperhidrosis) in three weight groups (normal, overweight, obese) and the number of dermatology visits. A total of 248,775 subjects were included. Bivariate analyses showed a higher proportion of insulin resistance disorders, bacterial infection, fungal infection, inflammatory disorders, mechanical changes, and other skin conditions in obese subjects than in subjects with a normal BMI (p