An outbreak of yellow fever with concurrent chikungunya virus transmission in South Kordofan, Sudan, 2005
An outbreak of yellow fever with concurrent chikungunya virus transmission in South Kordofan, Sudan, 2005
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DOI：
10.1016/j.trstmh.2008.04.014
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发表时间：
2008-12-01
影响因子：
2.2
通讯作者：
Perea, William
中科院分区：
文献类型：
--
作者：
Gould, L. Hannah;Osman, Magdi S.;Perea, William
2005年9月至12月，苏丹南科尔多凡州爆发出血热疫情。最初的实验室检测结果在患者样本中发现了IgM，即黄热病病毒抗体，11月14日宣布发生黄热病疫情。为了控制疫情，在南科尔多凡州部分地区开展了大规模疫苗接种运动，并实施了病媒控制。监测数据来自苏丹联邦卫生部。临床信息和血清样本是从爆发期间患病的一部分患者中获得的。游牧民、卫生人员和村长就疫情接受了采访。在北科尔多凡州和南科尔多凡州的11个村庄和城镇收集了蚊子。2005年9月10日至12月9日，共报告了605例与疫情有关的病例，其中45%发生在游牧民中。在Julud和Abu Jubaiyah诊所就诊的177名患者中，有29%患有与YF一致的疾病。18名未接种疫苗的近期患病者中有5人和16名未接种疫苗的无症状者中有4人出现YF病毒IgM抗体。在5名（27%）患病者和3名（19%）无症状者中检测到基孔肯雅病毒IgM抗体。这些结果表明，基孔肯雅热和YF都发生在暴发期间。由Elsevier Ltd代表皇家热带医学和卫生学会出版。
From September through December 2005, an outbreak of hemorrhagic fever occurred in South Kordofan, Sudan. Initial laboratory test results identified IgM, antibodies against yellow fever (YF) virus in patient samples, and a YF outbreak was declared on 14 November. To control the outbreak, a YF mass vaccination campaign was conducted and vector control implemented in parts of South Kordofan. Surveillance data were obtained from the Sudan Federal Ministry of Health. Clinical information and serum samples were obtained from a subset of patients with illness during the outbreak. Nomads, health personnel and village chiefs were interviewed about the outbreak. Mosquitoes were collected in 11 villages and towns in North and South Kordofan. From 10 September to 9 December 2005 a total of 605 cases of outbreak-related illness were reported, of which 45% were in nomads. Twenty-nine percent of 177 patients seen at clinics in Julud and Abu Jubaiyah had illness consistent with YF. Five of 18 unvaccinated persons with recent illness and 4 of 16 unvaccinated asymptomatic persons had IgM antibodies to YF virus. IgM antibodies to chikungunya virus were detected in five (27%) ill persons and three (19%) asymptomatic persons. These results indicate that both chikungunya and YF occurred during the outbreak. Published by Elsevier Ltd on behalf of Royal Society of Tropical Medicine and Hygiene.