Survival in systemic lupus erythematosus.
Survival in systemic lupus erythematosus.
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系统性红斑狼疮的存活率。
DOI：
10.1001/jama.1978.03280440025003
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发表时间：
1978
期刊：
影响因子：
--
通讯作者：
N. Hadler
中科院分区：
文献类型：
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作者：
D. Albert;N. Hadler
致编辑——我们赞扬 Urman 和 Rothfield (238:2272-2276, 1977) 对贝尔维尤医院和诊所以及康涅狄格大学医院和诊所跟踪的大量系统性红斑狼疮 (SLE) 病例进行的分析。尽管它增加了越来越多的文献支持狼疮患者的生存率正在改善的论点，但它并没有阐明生存率改善的原因。在本研究涵盖的这些年里，诊断和治疗方面有了许多改进。这些包括通过常规使用抗核抗体、多种新型抗生素、广泛使用腹膜透析和血液透析以及其他一般支持措施来更容易地筛查狼疮。诊断改变的效果是通过纳入病情较轻且预后较好的患者来扩大系统性红斑狼疮患者的范围。此外，新的治疗措施提高了大多数患者的机会
To the Editor.— We commend Urman and Rothfield (238:2272-2276, 1977) for their analysis of the large groups of cases of systemic lupus erythematosus (SLE) followed at Bellevue Hospital and Clinic and the University of Connecticut Hospital and Clinics. Although it adds to a growing literature that supports the contention that the survival of patients with lupus is improving, it does not clarify the reasons for this improved survival. There were many improvements in diagnosis and therapy during the years that this study covered. These included easier screening for lupus with the routine use of the antinuclear antibody, multiple new antibiotics, widespread use of peritoneal dialysis and hemodialysis, and other general supportive measures. The effect of the diagnostic changes was to widen the pool of patients with SLE by including patients who were less ill and had better prognoses. In addition, the new therapeutic measures improved the chances of the most