Accuracy of the triglyceride to high-density lipoprotein cholesterol ratio for prediction of the low-density lipoprotein phenotype B

Accuracy of the triglyceride to high-density lipoprotein cholesterol ratio for prediction of the low-density lipoprotein phenotype B
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DOI:
10.1016/j.amjcard.2004.03.069
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发表时间:
2004-07-15
影响因子:
2.8
通讯作者:
Bittner, V
Bittner, V
中科院分区:
医学3区
文献类型:
--
作者:
Hanak, V;Munoz, J;Bittner, V

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本研究检验了甘油三酯/高密度脂蛋白 (HDL) 胆固醇比率 3.8 预测低密度脂蛋白 (LDL) 表型 B 的准确性。3.8 的比率是基于成人治疗小组对正常空腹甘油三酯 (< 150 mg/dl) 和 HDL 胆固醇 (> 40 mg/dl) 的建议。从 658 名患者身上采集了空腹血样。通过核磁共振波谱法进行LDL表型分析。甘油三酯/HDL胆固醇比率为3.8除以LDL表型分布,其中79%(95%置信区间[CI] 74至83)的表型B大于该比率,81%(95% CI 77至85)的表型A小于3.8的比率。该比率对于识别男性和女性的 LDL 表型 B 是可靠的。 (C) 2004 年,Excerpta Medica, Inc.
This study examined the accuracy of a triglycericle/high-density lipoprotein (HDL) cholesterol ratio of 3.8 for the prediction of low-density lipoprotein (LDL) phenotype B. The ratio of 3.8 was based on Adult Treatment Panel recommendations for normal fasting triglycerides (< 150 mg/dl) and HDL cholesterol (> 40 mg/dl). Fasting blood samples were obtained from 658 patients. LDL phenotype analysis was performed by nuclear magnetic resonance spectroscopy. A triglyceride/HDL cholesterol ratio of 3.8 divided the distribution of LDL phenotypes with 79% (95% confidence interval [CI] 74 to 83) of phenotype B greater than and 81% (95% CI 77 to 85) of phenotype A less than the ratio of 3.8. The ratio was reliable for identifying LDL phenotype B in men and women. (C) 2004 by Excerpta Medica, Inc.