L and M cone proportions in polymorphic New World monkeys.
L and M cone proportions in polymorphic New World monkeys.
复制标题
多态性新世界猴的 L 和 M 锥体比例。
DOI：
10.1017/s0952523806233066
复制
发表时间：
2006
期刊：
影响因子：
--
通讯作者：
Williams,GaryA
中科院分区：
文献类型：
--
作者：
Jacobs,GeraldH;Williams,GaryA
阔鼻猴通常只有一个X染色体视蛋白基因。该基因的等位基因编码中长波长锥状色素的多个版本。X染色体失活为杂合子女性提供了含有M和L两种类型色素的视锥细胞的视网膜镶嵌，从而建立了三色色觉的色素基础。本研究检查了由该过程产生的L和M视锥细胞的比例。为此目的，视网膜电图闪烁光度法获得完整的光谱灵敏度函数从60杂合子雌性猴子从7属的阔鼻猴。为了获得估计的锥比例，这些功能随后拟合与线性组合的L和M锥的基本原理，来自同类动物只有一种类型的M/L色素的类似记录。与随机X染色体失活过程一致，整个样品的平均L：M锥加权接近1。与此同时，在L：M锥比例有显着的个体差异。这种变化的成因和它的影响，看到的讨论。
Platyrrhine monkeys typically have only a single X-chromosome opsin gene. Alleles of this gene code for multiple versions of middle- to long-wavelength cone photopigments. X-chromosome inactivation provides heterozygous females with a retinal mosaic of cones containing either of two types of M and L pigment, thus establishing the photopigment basis for trichromatic color vision. This study examined the proportions of L and M cones created by this process. For that purpose, electroretinogram flicker photometry was used to obtain complete spectral sensitivity functions from 60 heterozygous female monkeys drawn from seven genera of platyrrhine monkeys. To obtain estimates of cone proportions, these functions were subsequently fit with linear combinations of L and M cone fundamentals that were derived from similar recordings made on conspecific animals having only one type of M/L pigment. Consistent with a random X-chromosome inactivation process, the average L:M cone weighting across the sample was close to unity. At the same time, there were significant individual variations in L:M cone proportions. The genesis of this variation and its implications for seeing are discussed.